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Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma.
du Chatinier A, Meel MH, Das AI, Metselaar DS, Waranecki P, Bugiani M, Breur M, Simonds EF, Lu ED, Weiss WA, Garcia Vallejo JJ, Hoving EW, Phoenix TN, Hulleman E. du Chatinier A, et al. Among authors: metselaar ds. Neurooncol Adv. 2022 May 24;4(1):vdac079. doi: 10.1093/noajnl/vdac079. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 35733514 Free PMC article.
MEK/MELK inhibition and blood-brain barrier deficiencies in atypical teratoid/rhabdoid tumors.
Meel MH, Guillén Navarro M, de Gooijer MC, Metselaar DS, Waranecki P, Breur M, Lagerweij T, Wedekind LE, Koster J, van de Wetering MD, Schouten-van Meeteren N, Aronica E, van Tellingen O, Bugiani M, Phoenix TN, Kaspers GJL, Hulleman E. Meel MH, et al. Among authors: metselaar ds. Neuro Oncol. 2020 Jan 11;22(1):58-69. doi: 10.1093/neuonc/noz151. Neuro Oncol. 2020. PMID: 31504799 Free PMC article.
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Balakrishnan I, Danis E, Pierce A, Madhavan K, Wang D, Dahl N, Sanford B, Birks DK, Davidson N, Metselaar DS, Meel MH, Lemma R, Donson A, Vijmasi T, Katagi H, Sola I, Fosmire S, Alimova I, Steiner J, Gilani A, Hulleman E, Serkova NJ, Hashizume R, Hawkins C, Carcaboso AM, Gupta N, Monje M, Jabado N, Jones K, Foreman N, Green A, Vibhakar R, Venkataraman S. Balakrishnan I, et al. Among authors: metselaar ds. Cell Rep. 2020 Oct 20;33(3):108286. doi: 10.1016/j.celrep.2020.108286. Cell Rep. 2020. PMID: 33086074 Free PMC article.
Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma.
Meel MH, de Gooijer MC, Metselaar DS, Sewing ACP, Zwaan K, Waranecki P, Breur M, Buil LCM, Lagerweij T, Wedekind LE, Twisk JWR, Koster J, Hashizume R, Raabe EH, Montero Carcaboso Á, Bugiani M, Phoenix TN, van Tellingen O, van Vuurden DG, Kaspers GJL, Hulleman E. Meel MH, et al. Among authors: metselaar ds. Clin Cancer Res. 2020 Jul 1;26(13):3319-3332. doi: 10.1158/1078-0432.CCR-19-3538. Epub 2020 Mar 12. Clin Cancer Res. 2020. PMID: 32165429